|| Bordetella pertussis|
||Genus name: named after the Belgian microbiologist Jules Bordet (1870-1961), who first isolated B. pertussis.
Species epithet: severe cough (whooping cough).
|Significance:|| [Primarily in human medicine]
||18-232 = ATCC 9797 = CCUG 30873 = NCTC 10739|
|Form small pinpoint white shiny colonies (appr. diameter 1 mm), which give hemolysis on blood agar.
||Small non motile coccoid rods (0.2-0.5 x 0.5-1 µm), which appear singly, in pair or more rarely in chains.
|Gram +/Gram -:||G-
|Fermentation of carbohydrates:
||Bordetella spp. does not ferment carbohydrates.
||Optimal growth temperature: 35-37°C.|
|Disease (English):||Pertussis, whooping cough|
||Runny nose, sneezing, coughing (whooping cough) and fever. Adults get milder symptoms than children.|
||Filamentous hamagglutinin which anchors the bacteria to cilia. A tracheal cytotoxin, which inhibits the movement of the cilia, is then produced. Lipopolysaccharide (LPS), which is an endotoxin. Pertussis toxin (PT) which is an AB5-type exotoxin, helps the bacteria to colonize the respiratory tract. PT is secreted by a type IV secretion system.|
|NC_002929 ||Tohama 1 ||4 086 189 ||1c + 0 |
|16S rRNA Seq.:
|Acc-no||Strain||Number of NT||Operon|
|U04950 ||(T) ||1464 ||3 |
|Eight species have been described within genus Bordetella. The four species, which are described in VetBact, are very closely related.
|Comment:||B. pertussis is easily spread by coughing and the incubations period is 1-2 weeks.|