|| Leptospira interrogans|
||Genus name: thin helix (coil). |
Species epithet: interrogation (refers to the shape resembling a question mark).
|Significance:||Leptospirosis is said to be the most wide spread zoonotic infection in Nature.
||Serovar Icterohaemorrhagiae, RGA = ATCC 23581.|
||"Sewing thread thin" (0.1 x 6-12 µm), helical and with a hook on each end. Motile and has two periplasmic flagella.
|Gram +/Gram -:||G-
|Fermentation of carbohydrates:
||Does not ferment karbohydrates.
||Generation time: 6-8 h. Optimal growth temperature: 28-30°C.|
||Dog, cattle and pig etc. as well as humans.|
|Disease (Swedish):||Leptospiros, som är en zoonos.
|Disease (English):||Leptospirosis, which is a zoonosis.|
||Fever, renal and hepatic insufficiency as well as pulmonary manifestations and reproductive failure. |
Chrom I (4.277.185 bp) and chrom. II (350 181 bp), respectively.
|AE016823 and AE016824 ||Fiocruz L1-130 (Serovar Copenhageni) ||4 627 366 ||2c + 0 |
|16S rRNA Seq.:
Two rRNA genes on chrom. I and none on chrom. II.
|Acc-no||Strain||Number of NT||Operon|
|Z12817 ||Serovar Icterohaemorrhagiae, RGAT ||1 396 ||2 |
|About 25 different species have been described within the genus Leptispira. L. interrogans is closely related to L. kirschneri. See the phylogenetic tree (Fig. 116:1).
||Leptospirosis is notifyable in Sweden|
|Comment:||There are 23 different serogroups, which in turn are divided into about 250 different serovars. Icterohaemorrhagiae and Bratislava are important serovars. From a clinical point of view, the serovar is more important than the species as pathogenicity is associated with serovar, rather than species and different species may belong to the same serovar.|
||No. 6, 36, 41, 109|
||The Leptospirosis Information Center|