|| Dichelobacter nodosus|
||Genus name: rod shaped (bacterium) in ungulates.
Species epithet: full of knots (refers to the shape of the cells).|
|Significance:||The disease causes economic losses and animal suffering in large parts of the world.
|Old Species Name(s):||Bacteroides nodosus|
||ATCC 25549 = CCUG 27824.|
|Small (0.5-3.0 mm in diameter) translucent grayish white colonies after 3-7 days. Grows slowly and the colonies are difficult to see. Gives no hemolysis on FAA plates.
||Straight or curved rods (1-1.7 x 3-6 µm) with rounded and enlarged ends. Has twitching motility by means of type IV pili.
|Gram +/Gram -:||G-
||DNase -, esculinase -, ornithine decarboxylase +, tryptophanase (indole) -, urease -.
|Fermentation of carbohydrates:
||D. nodosus does not ferment carbohydrates.
||Hoof agar is often used for isolation of D. nodosus.
||Sheep, goat, cattle|
|Disease (Swedish):||Fotröta. Man brukar skilja på benign (mild) och virulent (allvarlig) fotröta beroende på hur allvarliga symtomen är.
|Disease (English):||Footrot. One usually distinguish between benign (mild) and virulent (severe) footrot depending on how severe the symptoms are. These two disease conditions are also referred to as interdigital dermatitis (ID) and under-running footrot, respectively.|
||Lameness and reduced productivity due to inflammation of the epidermis in the hoof tissue.|
||Type IV pili (fimbriae) which give the bacteria motility in damaged tissue. Extracellular serine protease which makes it possible for the bacterium to digest the tissue of the host animal to get access to free amino acids.|
|Diagnostics:||Gram staining of clinical material, microscopy, culture and confirmation by PCR or MALDI-TOF MS. Benign strains can be differentiated from virulent ones by PCR.|
|NC_009446 ||VCS1703A ||1 389 350 || |
|16S rRNA Seq.:
|Acc-no||Strain||Number of NT||Operon|
|DQ016290 ||AN 363/05 ||1437 ||3 |
||No. 2, 39, 127|